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Moreover, expression levels of neuronal differentiation 1 ( NEUROD1 ), which is a transcription factor with a critical role in cell fate and maturation (47), follow similar patterns to the aforementioned genes, with the highest expression in the -4 subcluster (Figure 3D)

These findings emphasize the importance of incorporating exercise into the treatment plan for PCOS, highlighting its potential to improve the overall health and quality of life of affected individuals